The River Room,recently restored, illustrates the history of Port Republic as a typical colonial riverport from its settlement in the mid-1700's to its peak as a major river port and booming industrial town when fleets of barges set off for Harper's Ferry or Baltimore.

The Turner Ashby Room describes Port Republic as the site of the last days of Stonewall Jackson's Valley Campaign, including the death of General Turner Ashby, Jackson's narrow escape during an invasion of the village, and the battles of Cross Keys and Port Republic. (Exhibits now in place.)

The Keeping Room, now under renovation, is used to interpret the town’s postwar history, and the cultural development from an industrial village to a residential community resulting from the ravages of war and floods and the growth of roads and railroads.